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Clinical trials for Metabolic Processes

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    307 result(s) found for: Metabolic Processes. Displaying page 1 of 16.
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    EudraCT Number: 2016-001661-91 Sponsor Protocol Number: ML19569 Start Date*: 2016-12-09
    Sponsor Name:F. Hoffmann-La Roche AG
    Full Title: Open-label Comparative Randomized Study of the Efficacy and Safety of Orlistat (Xenical) in Complex Therapy of Obesity and Metabolic Disorders in Adolescents
    Medical condition: Obesity in combination with metabolic disorders
    Disease: Version SOC Term Classification Code Term Level
    19.0 10027433 - Metabolism and nutrition disorders 10058097 Metabolic disorder PT
    19.0 10027433 - Metabolism and nutrition disorders 10029883 Obesity PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: (No results available)
    EudraCT Number: 2012-000432-26 Sponsor Protocol Number: versie1,dd01-02-2012 Start Date*: 2012-09-26
    Sponsor Name:Maastricht University Medical Centre
    Full Title: Prospective study on the metabolic and linear growth effects of growh hormone treatment in children with Kabuki Syndrome
    Medical condition: Kabuki Syndrome (KS, OMIM 147920) with a mutation in MLL2 gene.
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-002037-38 Sponsor Protocol Number: NL44415.078.13 Start Date*: 2013-10-29
    Sponsor Name:
    Full Title: The effect of correction of metabolic acidosis in chronics kidney disease on intrarenal RAS activity.
    Medical condition: Metabolic acidosis in chronic kidney disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-000199-86 Sponsor Protocol Number: 2015-000199-86 Start Date*: 2015-04-29
    Sponsor Name:University of Copenhagen, The Novo Nordisk Foundation Center For Basic Metabolic Research, section of Metabolic Genetic
    Full Title: Effects of metformin on human gut microbiota
    Medical condition: Young healthy men
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10062192 Metabolic function test normal PT
    20.0 10022891 - Investigations 10053075 Microbiology test PT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-000677-77 Sponsor Protocol Number: S61338 Start Date*: 2018-06-26
    Sponsor Name:University Hospital Leuven
    Full Title: Novel strategies in weight loss in women with polycystic ovary syndrome: does the gut microbiome play a role?
    Medical condition: overweight and obese women with polycystic ovary syndrome (PCOS) at risk for metabolic syndrome
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2016-001850-16 Sponsor Protocol Number: 2016-001850-16 Start Date*: 2016-06-28
    Sponsor Name:University of Copenhagen, The Novo Nordisk Foundation Center For Basic Metabolic Research, Section of Metabolic Genetic
    Full Title: Studies of interplays between insulin resistance associated with immunosuppression and the gut and saliva microbiota composition of young, healthy men
    Medical condition: Young healthy men
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10062026 Investigation PT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-002638-36 Sponsor Protocol Number: 1aa Start Date*: 2020-03-03
    Sponsor Name:Bispebjerg Hospital, University of Copenhagen
    Full Title: Glucagon Dose-response Relationship for Cardiovascular Activity A Randomized, participant-blinded, Crossover Study
    Medical condition: Glucagon-induced changes in heart rate, blood pressure, cardiac output. and metabolic effects
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-004846-25 Sponsor Protocol Number: Pfizer-Prevenar13-2015 Start Date*: 2016-07-15
    Sponsor Name:Maastricht University
    Full Title: Immunization against oxLDL in patients with lysosomal lipid diseases and associated metabolic disorders
    Medical condition: Familial hypercholesterolemia Niemann-Pick disease type B (NPB) Niemann-Pick disease type C (NPC) Partial lipodystrophy in children and adults
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-002220-32 Sponsor Protocol Number: 225/2611 Start Date*: 2012-06-13
    Sponsor Name:OYS
    Full Title: The effects of contraceptive pill and hormonal vaginal ring on hormonal, inflammatory and metabolic parameters in women of reproductive age with polycystic ovary syndrome (PCOS).
    Medical condition: Polycystic Ovary Syndrome (PCOS)
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003910-26 Sponsor Protocol Number: 01/2015 Start Date*: 2017-12-11
    Sponsor Name:Núcleo de Estudos de Hipertensão da Beira Interior
    Full Title: Fase II, unicenter, open, randomized trial to evaluate the response of Th17 and T regulatory lymphocytes to 24 weeks supplementation with cholecalciferol in patients with arterial hypertension, obe...
    Medical condition: Obesity associated arterial hypertension Metabolic syndrome associated arterial hypertension
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: PT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004755-21 Sponsor Protocol Number: CHUBX2012/17 Start Date*: 2016-03-15
    Sponsor Name:CHU de Bordeaux
    Full Title: Multicenter double-blind randomized clinical trial assessing efficacy and safety of exenatide in the treatment of hypothalamic obesity after craniopharyngioma therapy.
    Medical condition: Hypothalamic obesity after craniopharyngioma therapy.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-003430-85 Sponsor Protocol Number: OBERAL Start Date*: 2017-11-29
    Sponsor Name:Helsinki University Hospital
    Full Title: A randomized, open, parallel design study to evaluate the effect on liver fat, adipose tissue and metabolic parameters when switching a protease inhibitor or efavirenz to once daily raltegravir in ...
    Medical condition: Study subjects are HIV infected patients with BMI>25kg/m2 and who have at least one metabolic syndrome component or a fatty liver disease.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2013-004782-14 Sponsor Protocol Number: THIGHT_2 Start Date*: 2014-03-20
    Sponsor Name:Medizinische Universität Wien, KIMIII, Abteilung für Endokrinologie und Stoffwechsel
    Full Title: Assessment of changes in metabolic activity in liver & skeletal muscle in patients suffering from acromegaly - a 31P/1H magnetic resonance spectroscopy pilot study
    Medical condition: Acromegaly
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-002987-26 Sponsor Protocol Number: KOLterbutaline Start Date*: 2011-08-24
    Sponsor Name:Bispebjerg Hospital
    Full Title: Effects of high dose terbutaline on physical performance in patients with chronic obstructive pulmonary disease and acute inflammatory response after exercise
    Medical condition: To investigate the effects of terbutaline on repeated exercise performance in patients with chronic obstructive pulmonary disease (COPD). Furthermore to examine the inflammatory response during and...
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2022-000404-35 Sponsor Protocol Number: 80519 Start Date*: 2022-07-26
    Sponsor Name:AMC, Cardiovascular Sciences
    Full Title: Does the hematopoietic stem cell govern residual inflammatory cardiovascular risk in type 2 diabetes?
    Medical condition: Inflammation in patients with type 2 diabetes
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-000152-19 Sponsor Protocol Number: 1 Start Date*: 2022-02-24
    Sponsor Name:Consorcio Centro de Investigación Biomédica en Red, M.P. (CIBER)
    Full Title: Control strategies and pharmacogenetic study for the personalized treatment of fatty liver associated with metabolic dysfunction in patients with prediabetes.
    Medical condition: Metabolic Associated Fatty Liver Disease with prediabetes.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-003823-14 Sponsor Protocol Number: CDCA-PK Start Date*: 2021-11-16
    Sponsor Name:Amsterdam UMC
    Full Title: Pharmacokinetic cross-over study of compounded chenodeoxycholic acid.
    Medical condition: CTXCT
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-003566-13 Sponsor Protocol Number: GLP1-hypofyse Start Date*: 2019-01-02
    Sponsor Name:Radboud university medical center
    Full Title: iPAVE – imaging Pituitary ActiVation by Exendin
    Medical condition: Type 2 diabetes
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-004123-19 Sponsor Protocol Number: MUN-391-LOR-0050-I Start Date*: 2006-01-24
    Sponsor Name:Klinikum rechts der Isar der Technischen Universitaet Muenchen
    Full Title: Metabolic Response Evaluation for an Individualization of Neoadjuvant Chemo- and Radiotherapy in Esophageal Adenocarcinoma
    Medical condition: This study will test an optimized therapy for patients with chemotherapy-resistent locally advanced adenocarcinomas at the gastro-esophageal junction. According to the protocol, patients should re...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-005404-17 Sponsor Protocol Number: TAO-EX-2012 Start Date*: 2013-01-16
    Sponsor Name:Center for Neuropsychiatric Schizophrenia Research
    Full Title: Treatment of antipsychotic associated obesity with a GLP-1 Analogue: the TAO study
    Medical condition: Obesity
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
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